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Ascension Health Ventures, LLC (AHV) was launched
in 2001 as a subsidiary of Ascension Health, the largest nonprofit
Catholic healthcare system in the United States. Through AHV, Ascension
Health provides strategic venture funding to companies that offer
healthcare-related products, services or technologies that represent
potential service breakthroughs for Ascension Health’s hospitals
and health facilities and contribute to the transformation of healthcare.
Ascension Health Ventures also partners with select healthcare venture
capital funds to achieve portfolio diversification.
In order to be considered for an AHV investment,
companies and other venture funds must be consistent with Ascension
Health’s Mission, Vision and Values. The products or services
of the portfolio companies must also provide clinical, operational
and/or financial value to the System. Ascension Health Ventures
targets later-stage development companies that have clear momentum.
Key attributes of an opportunity include experienced management,
fully-developed products or services with an existing customer base,
formalized business plans with documented value propositions, prior
financing and identified exit strategies.
www.ascensionhealthventures.org
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Founded in 1979, Advanced Technology Ventures (ATV)
is a bi-coastal venture capital firm with more than $1.5 billion
in capital under management. We work closely with entrepreneurial
teams in several technology markets, including communications, IT
infrastructure, software and services, and healthcare technologies,
to build emerging-growth business ventures into market leaders.
With more than 20 years of experience, ATV has a proven track record
of success in helping to build strong, sustainable business enterprises.
What Sets ATV Apart:
- Extensive Operational Experience: Our experienced
investment professionals have decades of first-hand experience
launching successful businesses and growing private and public
companies. In fact, six ATV partners have either founded companies
or been CEOs.
- Intellectual Capital: ATV's global resources
in industry, academia, government, financial, and venture capital
guide our portfolio companies through their most critical stages
of development. Our portfolio companies also benefit from access
to ATV Technology Partners, world-renowned information technology
and healthcare visionaries.
Successful Track Records:
Over the years, ATV has a proven history in supporting over 30 companies
from inception to IPO or acquisition, representing billions of dollars
in market value. Examples include Accord Networks, Actel, Berkeley
Networks, Credence Systems, Cytyc, DataSage (Vignette), Docent,
Epigram (Broadcom), Novoste, Seagull Software and WebLine Communications
(Cisco).
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Advent International is one of the world’s
largest private equity firms with $6 billion in cumulative capital
raised* and offices in 13 countries. We are unique. No other private
equity firm has our combination of industry expertise, international
resources and local market knowledge. Since our founding in 1984,
we have invested in over 500 companies in 35 countries and have
helped businesses raise $10 billion through public equity and debt
offerings. These include 128 IPOs on major stock exchanges worldwide.
We apply our wealth of experience, resources and expertise to help
build businesses of significant value around the globe.
www.adventinternational.com
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Atlas Venture is the leading international early-stage
venture capital firm, investing in communications, information technology
and life sciences companies. With investing offices in Boston, London,
Munich and Paris, Atlas Venture divides its investments between
the United States and Europe.
Founded in 1980, Atlas Venture has organized six
international funds, and currently manages $2.1 billion in committed
capital. The Atlas Venture investment team is comprised of seasoned
operating executives and career venture capitalists who have been
deeply involved in the formation and development of more than 300
companies worldwide. For more information about Atlas Venture, go
to www.atlasventure.com.
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Banc of America Securities LLC ("BAS"),
a subsidiary of Bank of America Corporation, is a full-service U.S.
investment bank and brokerage firm with principal offices in San
Francisco, New York, and Charlotte. Together with its U.K. affiliate,
Banc of America Securities Limited ("BASL"), the firm
delivers capital raising, financial advisory and risk management
solutions, bulge-bracket trading and global distribution services,
and objective research on global markets and growth sectors to corporations,
institutional investors, financial institutions and government entities.
BAS is a member of the following exchanges: New York Stock Exchange
(NYSE), National Association of Securities Dealers (NASD) American
Stock Exchange (AMEX), Boston Stock Exchange (BSE), Chicago Board
of Options Exchange (CBOE), Chicago Stock Exchange CHX), Cincinnati
Stock (CSE), International Securities Exchange (ISE), Pacific Stock
Exchange (PSE), Philadelphia Stock Exchange (PHLX) and is registered
as an international dealer with the Ontario Securities Commission.
BASL is a UK authorized credit institution, regulated
by the FSA under the Financial Services and Markets Act 2000 in
the UK. It is a company incorporated with limited liability in England
and Wales with registered number 01009248 and is a wholly owned
subsidiary of Bank of America, National Association ("BANA"),
headquartered in Charlotte, North Carolina, USA. BASL is a member
of the following exchanges: London Stock Exchange, Euronext Paris,
Euronext Amsterdam, and Borsa Italiana.
BAS and BASL are subsidiaries respectively of Bank
of America Corporation ("BAC"). BAC is one of the world’s
leading financial services companies, with more than 140,000 associates,
offices in 32 countries and client solutions spanning 190 countries.
The company’s stock (ticker: BAC) is listed on the New York,
Pacific and London stock exchanges, and certain shares are listed
on the Tokyo Stock Exchange. For more information about BAC’s
corporate and institutional capabilities, visit www.bofa.com.
For information about BAC’s extensive consumer banking franchise,
visit www.bankofamerica.com.
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Founded in 2000, Beyond Genomics is an emerging
biotechnology company that applies its proprietary Systems Biology
platforms to develop novel therapeutics and biomarkers (BioSystem
Markers™) . Current approaches such as genomics and proteomics
focus on one aspect of biological systems at a time. Rather than
ignoring or over-simplifying the inherent complexity of biological
processes that underlie human diseases or that govern drug responses,
Beyond Genomics has pioneered the creation of Molecular Phenotypes™
to enable biological research at the systems level. Molecular Phenotyping™
involves measuring complex biological samples, including simultaneously
measuring transcripts, proteins and metabolites, and integrating
these data sets with clinical information. Tracking changes in Molecular
Phenotypes™ can improve multiple aspects of pharmaceutical
discovery and development, including drug safety and efficacy, drug
response, and the etiology of disease. BG’s Systems Biology
platform integrates state-of-the-art technologies in proteomics,
metabolomics, and bioinformatics. The company has also developed
a proprietary BioSystematics™ data integration and knowledge
management platform that generates connections, correlations, and
relationships among thousands of measurable molecular components.
www.BeyondGenomics.com.
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BioEnterprise Asia is an Asia-Pacific life science
technology management company. The company operates 3 complementary
and synergistic businesses:
- - a consulting and advisory practice dedicated
to working with leading international and regional life science
technology players to establish and successfully expand high growth
operations and effective strategic alliances in the region;
- a technology business incubation practice dedicated
to accelerating the development of innovative life science technologies
and technology enterprises;
- and an education/market research/event management
practice dedicated to helping to raise awareness and understanding
of the potential and opportunity that life science and biotechnology
offer for catalyzing economic and social development in Asia and
beyond.
www.bioenterprise.org
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Biotech Consortium India Ltd (BCIL), a company promoted
by the Department of Biotechnology (DBT), Government of India and
the all India financial institutions and corporate sector as the
share holders, works for accelerated development and commercialization
of biotechnology in India. For this purpose, it brings together
industry and R & D institutions to facilitate translation of
research into commercial ventures, provides consultancy to industry,
government and international organizations to take forward biotechnology
activities and creates awareness throughout the nation by information
dissemination on significant current developments in the area.
During the last ten years, the company has transferred
many key technologies including diagnostics for HIV 1 and 2, Alphafetoprotein,
Dengue, Japanese encephalitis and Hepatitis A and recombinant anthrax
vaccine. It has provided consultancy assistance to more than 150
clients so far by preparing diversification plans, feasibility reports,
project reports, market surveys and sectoral studies. It has also
developed business plans for setting up Biotechnology Parks and
Centres of Excellence in Biotechnology for many state governments
and other development agencies.
In recognition of its contributions, the company
was honoured with a special national award on Biotech Product and
Process Development and Commercialization in 2001.
In the coming years, the company plans to catalyze biotechnology
investments by providing an integrated package of services to prospective
entrepreneurs covering identification of appropriate projects and
technologies, preparation of business plans and project reports,
fund syndication and turn key implementation. For these, it would
take up new activities such as management of venture capital fund,
facilitation of regulatory approvals and infrastructure planning.
www.biotech.co.in
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Boston Millennia Partners has a long and successful
history of venture capital investing on a national scope. Our Core
Company Investment Strategy, combined with our international network
of relationships and our deep industry expertise, sets us apart
and enables us to add value to our portfolio companies.
We look for investment opportunities within four
high growth industries:
• Healthcare
• Life Sciences
• Telecommunications
• IT & Business Services
We seek to partner with entrepreneurs who share
our goal of building enduring, large-scale businesses that result
in personal fulfillment and superior financial returns. Over the
past twenty years, we have developed an investment approach that
centers on active participation with our portfolio companies. Our
goal is to be valuable and effective investors, while at the same
time establishing productive relationships with our business partners
that create long-term value. For more information, see our “What
We Look For” section.
Our investing philosophy is guided by our Core Company
Investment Strategy, which accelerates the growth of a company through
strategic consolidation within an industry. By following a targeted
merger and acquisitions plan, a core portfolio company can quickly
increase its scale and broaden the scope of its product and service
offerings. The result is a company that replicates a proven business
model around an existing core platform to build a large, high-growth
enterprise. Within the past twenty years, core companies in our
portfolio have completed over 160 strategic acquisitions.
The growth and success of our portfolio companies
have, in turn, allowed us to grow and expand our capital base to
over $700 million. As our firm has grown, we have built a worldwide
network. Investors from over a dozen countries have entrusted us
to manage capital on their behalf.
www.millenniapartners.com
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Burrill & Company is a life sciences merchant
bank focused exclusively on companies involved in biotechnology,
pharmaceuticals, diagnostics, devices, human healthcare and related
medical technologies, nutraceuticals and wellness, agricultural
biotechnology, and industrial biotechnology (biomaterials/bioprocesses)
with over $500 million under management. Burrill's technical and
venture investing competence spans the entire spectrum of life sciences.
The expertise of the firm's investment team, strategic partners
and Advisory Boards is unparalleled in depth and breadth. In addition,
Burrill is a leader in life science strategic partnering, an invaluable
practice to build value in portfolio companies and to accelerate
their growth and development. Burrill is also the sponsor and facilitator
of three leading annual industry conferences and publishes the seminal
annual report on the state of the biotechnology industry. This combination
of resources and capabilities has helped Burrill develop a unique
and highly effective platform for finding and making outstanding
life science investments.
www.burrillandco.com
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Founded in 1995 as a subsidiary of the Caisse de
dépôt et placement du Québec (CDP), CDP Capital
- Technology Ventures (formerly CDP Sofinov), is a technology venture
capital (VC) firm with an established presence in North America
and, more recently, in Europe. CDP Capital - Technology Ventures
assets under management have a market value of CDN$1.6 billion.
Since its inception, it has invested in more than 160 privately
owned technology companies in the following investment sectors:
Biotechnology and Life Sciences, Information Technologies and Industrial
Technologies.
Mission
The mission of CDP Capital - Technology Ventures is to be a leading
VC investor with the ability to create added value for innovative
technology companies. With this objective in mind, we accompany
our portfolio companies in every stage of their development - from
seed to development stage, marketing, mergers, acquisitions, IPOs
and even beyond. Our high involvement creates a competitive edge
for our investee companies.
An expert team
Our team consists of skilled professionals with extensive financial
and operational expertise. They have an in-depth knowledge of the
sectors in which CDP Capital - Technology Ventures is involved.
They provide a source of knowledge and technical assistance to innovative
technology companies demonstrating strong potential for growth.
CDP Capital
CDP Capital, the largest asset manager in Canada, has more than
CDN$133 billion in total assets under management and oversees the
activities of CDP Capital – World Markets, CDP Capital –
Private Equity and CDP Capital – Real Estate Group. With its
experienced managers in global markets, CDP Capital provides CDP
and other clients in Canada and around the world with the most comprehensive
range of products and fund management services.
www.cdpcapital.com/technologyventures
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Chipscreen Biosciences Ltd, established on March
21, 2001 in Shenzhen with initial seed-capital of $5.8 million US
dollars from investors across Asia, is a drug discovery company
specialized in novel small molecule therapeutics. Chipscreen has
developed a proprietary chemical genomics approach to accelerate
the discovery of new medicines from its collections of natural products,
traditional medicines, and synthetic chemical libraries. Central
to its drug discovery platform is the company's capability of integrating
in silico design, chemistry, unique parallel multi-targets high
throughput screening, global gene expression profiling, and informatics
to rapidly and effectively advance the drug discovery process.
As the leading drug discovery startup company in China, Chipscreen
focuses on lead discovery and optimization of transcription modulators
for type II diabetes, cancer, and osteoporosis. Chipscreen also
provides services, including assay development, microarray analysis
and combinatorial chemistry, as a part of its drug discovery collaborations
to other pharmaceutical companies and academic institutions. Chipscreen
has assembled an impressive core team of outstanding experts in
drug discovery, biochips, biomedical research, medicinal chemistry,
bioinformatics, and chemoinformatics.
Members of the core team have published more than
200 peer-reviewed papers in related scientific journals including
Nature, Science, Nature Medicine and Nature Biotechnology. The team
has also published 4 books and has been awarded more than 20 international
patents in the areas of biochips and novel small molecule therapeutics.
They have identified 4 novel compounds that have entered FDA- and
EMEA-approved clinical trials and have developed 6 biological research
products that are being sold worldwide
Chipscreen's Core Advantages:
• A leading integrated technology platform for novel drug
discovery, world-class expert knowledge of biochip, in vitro models
of molecular medicine, high throughput drug screening, chemo- and
bioinformatics;
• A core managing team with international experience, familiarity
with requirements of drug entry into global market, and highly efficient
operating system with flexibility and quick response;
• Successful new drug research and development experience,
in-depth molecular medical knowledge of endocrinosis, inflammation
in immune system, cancer and other major diseases.
www.chipscreen.com
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Flagship Ventures is an early-stage venture capital
firm focused on creating, financing, and building companies in the
life science, information technology and communications sectors.
Flagship’s team of 23 professionals is among the most experienced
in the industry and represents a balance of venture capital, corporate
executive, and entrepreneurship expertise. The firm was founded
in 1999 and manages over $600 million on behalf of its institutional
and corporate investors. Headquartered in Cambridge, MA, Flagship
Ventures has been one of the most active early stage firms during
the last three-year, post-bubble period and has developed a portfolio
of over 40 high potential ventures.
For further information please visit www.flagshipventures.com.
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R.
Nelson Campbell,
Senior Vice President, Life Sciences Investment Banking
Friedman, Billings, Ramsey Group, Inc. provides investment
banking, institutional brokerage, asset management, and private
client services through its operating subsidiaries and invests in
mortgage backed securities and merchant banking opportunities. FBR
focuses capital and financial expertise on six industry sectors:
financial services, real estate, technology, healthcare, energy
and diversified industrials.
We believe that FBR occupies a unique position in the
capital markets. From our roots as a research boutique, we have
grown to a top 10 ranked national investment bank.
Our research, institutional brokerage and investment
banking services have placed us, with the Wall Street bulge bracket,
among the top 10 lead-managed equity underwriters* and among the
leading research-driven national brokerages, in the United States.
Yet, like a boutique, we achieve success through knowing our industries
extremely well. This proprietary thought process enables us to provide
independent research on small-cap to large-cap names, and to provide
creative capital to issuers. We focus across research, brokerage,
investment banking and asset management on six industry sectors:
financial services, real estate, technology, healthcare, energy
and diversified industrials. Our research analysts write on or have
detailed knowledge and understanding of the S&P 500 issuers
in their respective spaces, as well as small- and mid-cap companies.
Our process combines our deep understanding of individual
businesses in the context of their industries, with our significant
experience in the capital markets. This, along with our intelligent
institutional distribution, has enabled us to raise billions of
dollars of capital as a lead-managing underwriter, including in
transactions in excess of $500 million in size.
FBR, headquartered in the Washington, D.C. metropolitan
area, with offices in Arlington and Bethesda, also has offices in
Atlanta, Boston, Charlotte, Chicago, Cleveland, Denver, Irvine,
London, New York, Portland, San Francisco, Seattle, and Vienna.
FBR has elected REIT status for tax purposes. For more information,
see www.fbr.com.
Mailing address: Five Walpole Street, Norwood, Massachusetts
02062. Telephone: 781-762-9782; Fax: 781-769-9782.
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Founded in 1981, Genzyme today is one of the largest
and most well established biotechnology companies in the world.
With more than 25 major products and services marketed in over 60
countries, Genzyme is a global leader in the effort to develop and
apply the most advanced capabilities in biotechnology to address
a range of unmet medical needs.
Genzyme-sponsored research and development has led
to the introduction of new treatments for many serious health problems,
from rare and debilitating genetic diseases to renal disease, orthopaedic
injuries and the adverse effects of hypothyroidism. Building on
more than two decades of growth and success, the company’s
international R & D team and state-of-the art bioengineering
and manufacturing facilities are continually at work identifying
new opportunities to meet the health care challenges of the future.
With headquarters in Cambridge, Massachusetts, Genzyme
has approximately 5,500 employees working in 40 countries and annual
revenues of more than $1 billion. Under the umbrella of Genzyme
Corporation, the company is divided into three divisions, each representing
a major focus of the health care market in research, product development,
and patient care.
www.genzyme.com
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Global Life Science Ventures (GLSV) is an independent
venture capital firm dedicated exclusively to the life science industry.
With offices in Germany, Switzerland and the UK, GLSV focuses on
investments in early to late stage life science companies throughout
Europe and the U.S.. Its predecessor fund Global Life Science L.P.
advised by Life Science Ventures GmbH was founded in 1996 and raised
€ 66 million. GLSV II was launched in mid 2001 and raised €143million.
Our mission is to help building the value of our portfolio companies
by providing: introductions and key contacts to our network, help
in strategic decision making, aid in raising and structuring financing,
building appropriate syndicates, support in evaluating ongoing competitive
positioning and corporate deals.
To facilitate this, we have built a team of investment professionals
and experts that bring together a broad set of know-how and complementary
experience from top pharma & biotech management, life science
venture capital, R&D, academia, and consulting.
Selected Investments: Apovia, Artemis*, Axxima, Carex,
Coley Pharmaceutical Group, CombinatorX, Cyberkinetics,
Cytos*, EMBsolutions, Exelixis*, DeveloGen, Intercell, mbt Munich
Biotechnology, Memory, Neurogesx, Pieris, Sequenom*, Xantos.
(*Exits through IPO or trade sale)
Alliances: We have alliances with two US
venture capital funds, Oxford Bioscience Partners and TechAMP of
A.M. Pappas & Associates. In addition, we pro-actively build
strong investment syndicates with other leading international VC
funds for each investment.
www.glsv-vc.com
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Global Markets Capital Group, LLC is an independent
investment banking firm providing innovative strategic advisory
services and mergers and acquisitions expertise globally to public
and private companies. Through its advisory roles and its network
of global companies active in Europe, Asia, Australia and the US,
the firm has assisted numerous international life sciences and emerging
technology companies in achieving their strategic goals. The firm
has extensive M&A experience, specializing on international
and cross-border transactions, including:
• Mergers of public and private companies
• Stock and asset purchases
• Tender and exchange offers
• Restructurings and acquisitions
• Divestitures and spin-offs
• Leveraged buyouts and private equity investments
• Strategic investments and joint ventures
• Innovative equity products to access capital
To each engagement, GMCG, LLC brings independence,
rigorous analysis, cultural understanding and local experience.
It is this experience and application of our proven process that
culminates in the closure of successful transactions in the best
interests of our clients. A critical element in enabling European,
Asian, and Australian companies to take advantage of strategic opportunities
is our ability to access the US capital markets as a licensed NASD
broker/dealer.
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HarbourVest Partners, LLC is a global private equity
investment firm. It was founded in 1997 to assume the business of
Hancock Venture Partners, Inc., which was formed in 1982. HarbourVest
is 100%-owned by members of the investment team.
HarbourVest invests in all types of private equity
funds, including venture capital and leveraged buyout funds, and
also directly in operating companies. HarbourVest currently manages
investments in North America, South America, Europe, Asia, Australia
and Africa.
The Senior Managing Directors of HarbourVest Partners
have been investing together since 1979, and all 16 Managing Directors
have worked at HarbourVest or Hancock Venture Partners, Inc. for
an average of more than 14 years.
HarbourVest Partners is a limited liability company
that was formed in January 1997 by the former management of Hancock
Venture Partners, Inc. ("Hancock Venture Partners") to
assume the business of Hancock Venture Partners. Hancock Venture
Partners was founded in 1982 by the two Senior Managing Directors
of HarbourVest to provide institutional investors with a vehicle
through which to invest in venture capital and other private equity
partnerships as well as directly into operating companies.
The firm's clients include more than 200 pension
funds, endowments, foundations, and financial institutions from
the U.S., Europe, Canada, Australia, and Japan. During its 20-year
history of investing, the HarbourVest team has committed $7.9 billion
to 200 managers of private equity funds on a primary basis, completed
$1.3 billion in 210 purchases of secondary partnership interests,
and invested $1.9 billion directly in operating companies.
Since 1982, the management of HarbourVest has formed
six major investment programs to invest in the United States, the
most recent being HarbourVest Partners VI, a $4.6 billion investment
program formed in 1999 to invest in partnerships, buyout partnerships,
and direct investment opportunities. This fund is currently in an
active investment mode.
The management team is also responsible for forming
four investment programs focused exclusively on making private equity
investments outside the United States. HarbourVest International
Private Equity Partners IV was formed in 2002 with $2.8 billion
of capital, including $2.425 billion for partnership investments
and $375.0 million for direct investments. This fund is currently
in an active investment mode.
www.harbourvest.com
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Harvard Clinical Research Institute (HCRI) is a
joint venture of Harvard Medical School and its affiliated teaching
hospitals, including Brigham & Women’s Hospital, Beth
Israel Deaconess Medical Center and Massachusetts General Hospital.
HCRI’s mission is to improve health and quality-of-life by
collaborating with academic and industry partners to conduct high-quality
clinical research in a professionally nurturing and world class
academic environment.
HCRI draws on the experience of having conducted
over 100 medical device, pharmaceutical and biologic product trials
for domestic and international clients. Successful management of
cardiovascular, peripheral vascular, neurology and nephrology trials
has made HCRI an industry-leading CRO.
HCRI works with a team of Harvard thought-leaders
to provide cutting-edge trial design and data analysis, utilizing
the latest biostatistical methodologies. These individuals, most
of whom have appointments at Harvard Medical School and are well-published
in peer-reviewed journals, provide Sponsors with strategic planning
and strong scientific insight.
Driven by a skilled Project Management team, HCRI
also provides turnkey Data Management to Sponsors seeking a unique
academic-based CRO that is a leader in today’s global research
environment. HCRI’s services include database build, data
entry, data cleaning and a novel process for clinical event adjudication
that is highly regarded by industry.
HCRI’s staff of approximately 160 individuals
brings tremendous depth and experience to the conduct of clinical
research. Together, we seamlessly integrate world-class thought
leadership with industry responsiveness.
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The Office of Technology Licensing and Industry
Sponsored Research (OTL) mission is to facilitate the transfer of
inventions made by researchers at the Harvard Medical School and
the Harvard School of Dental Medicine to the private sector for
development of health care products that benefit the public. Towards
this end, we also seek to promote and establish fruitful research
collaborations with industry.
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Imperial Innovations (ICIL) is the wholly owned
technology transfer company of Imperial College, London.It is one
of the leading technology transfer offices in the UK and particularly
differentiates itself by focusing on providing extensive “hands
on” support to the process of creating new ventures and structuring
innovative financing arrangements to support their development.
Imperial Innovations has created over 50 technology-based ventures
since 1997, of which approximately half have been in the biotech
and medical devices field.
Imperial Innovations draws on the leading research
activities of Imperial College, which is consistently rated as one
of the top research-oriented universities in the UK and includes
one of Europe’s largest medical schools. Imperial College’s
Faculty of Medicine has campuses on 6 major NHS hospital sites and
works closely with the NHS in identifying and exploiting novel technologies,
and works closely with the other faculties in developing cross-disciplinary
initiatives in fields such as bioengineering, bioinformatics, research
technologies and medical devices.
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Infinity Pharmaceuticals, Inc., founded in February
2001, is a drug discovery com-pany that is developing and integrating
unique approaches and capabilities in synthetic chemistry, chemical
genetics, informatics, and biological screening.
The company is positioned to capitalize on the enormous
opportunity resulting from the genomics revolution by providing
pharmaceutically active and selective new drug candidates to a broad,
expanded range of well-validated biological targets.
Infinity is based on the scientific power of diversity-oriented
organic synthesis, informat-ics, and chemical genetic screening
of pathways and phenotypes. Novel chemistry accessed through diversity-oriented
synthesis generates molecules active and selective against a broader
range of targets, including those previously thought to be “non-druggable.”
Chemical genetic screening strategies enable exploration of the
entire range of possible drug targets in a non-biased manner. The
efficient integration of these two technologies, in combination
with advanced informatics and automation, yields expanded pools
of both validated drug targets and active drug candidates.
Infinity Pharmaceuticals, Inc.
780 Memorial Drive
Cambridge, MA 02139
Telephone: 617-453-1000
Fax: 617-453-1001
www.ipi.com.
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Established: 1887
Number of Staff/Employees: 2,700
Industry Sector: Fundamental Research in Health and Biology
Products/Services: Licensing Technologies
Mission: Private Institute Dedicated to Research and Public
Health
Business Strategy: Licensing technologies, patented by
the Institute Pasteur, to the Industry.
Financial Information: Non Profit Research Institute
Annual budget: $172 Million
The INSTITUT PASTEUR developement team operates
with the goal of licensing new technologies to industry in major
fields including: therapeutics, immunotherapy, cardiovascular, neurobiology,
diagnostics, vaccines, cancer, genomics, proteomics, bioinformatics,
microarray, gene therapy, agriculture, veterinary, biological material
(transgenic mice, strains, hybridomas, antibodies).
The INSTITUT PASTEUR, a private Institute dedicated
to Research and Public Health, was created in 1887 by Louis Pasteur.
Nowadays 2,700 staff and scientists are working on the campus in
Paris. 110 Research units, 10 WHO Collaborating centers and one
P4 laboratory are the essential resources of the Institute to conduct
a high quality Research focused on:
Infectious Diseases (AIDS, Hepatitis, SARS, Malaria, Meningitis,
Hemorrhagic fevers…), Molecular Biology, Genomics, Proteomics,
Bioinformatics, Immunology, Cancer and Neurobiology.
The INSTITUT PASTEUR is a non profit private Institute
and about 50 employees participate to the Business Development activity.
Based on a portfolio of 3,300 patents, the revenues from Licensing
of Technologies (Vaccines, Diagnostics and Therapeutics) represent
the major part of the Business development contribution which accounts
for 39% (73 Millions Euros) of the total budget of the Institut
Pasteur (188 Million Euros in 2002).
Major collaborations with industry have been already
established with: Aventis Pasteur, Bio-Rad, Glaxo Smith Kline, Roche,
Bayer etc…
The INSTITUT PASTEUR is nowadays increasingly licensing
technologies, in the above mentioned fields, to start-up and Biotech
companies.
The INSTITUT PASTEUR has contributed to the creation
of different start-up companies in its BioTop incubator : 1998 :
Hybrigenics (1998); Diatos (1999) ; Cellectis (1999); PasteurMediavita
(2000) ; Evologic (2000); Celogos (2001); Theraptosis (2001); BT
Pharma (2001) ; 2002 : Biocortech (2002) ; 2003 : Anaconda (2003)
.
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The International Finance Corporation (IFC) promotes
sustainable private sector investment in developing countries as
a way to reduce poverty and improve people’s lives.
IFC is a member of the World Bank Group and is headquartered
in Washington, DC. It shares the primary objective of all World
Bank Group institutions: to improve the quality of the lives of
people in its developing member countries. IFC Mission Statement.
Established in 1956, IFC is the largest multilateral
source of loan and equity financing for private sector projects
in the developing world. It promotes sustainable private sector
development primarily by:
- Financing private sector projects located in
the developing world.
- Helping private companies in the developing world
mobilize financing in international financial markets.
- Providing advice and technical assistance to
businesses and governments.
Ownership and Management
IFC has 176 member countries , which collectively determine its
policies and approve investments. To join IFC, a country must first
be a member of the IBRD. IFC’s corporate powers are vested
in its Board of Governors, to which member countries appoint representatives.
IFC’s share capital, which is paid in, is provided by its
member countries, and voting is in proportion to the number of shares
held. IFC’s authorized capital is $2.45 billion.
The Board of Governors delegates many of its powers
to the Board of Directors, which is composed of the Executive Directors
of the IBRD, and which represents IFC’s member countries.
The Board of Directors reviews all projects.
The President of the World Bank Group , James D.
Wolfensohn, also serves as IFC’s president. IFC’s Executive
Vice President, Peter Woicke, is responsible for the overall management
of day-to-day operations. Funding of IFC’s Activities
IFC’s equity and quasi-equity investments
are funded out of its net worth: the total of paid in capital and
retained earnings. Strong shareholder support, triple-A ratings,
and the substantial paid-in capital base have allowed IFC to raise
funds for its lending activities on favorable terms in the international
capital markets.
www.ifc.org.
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The mission of the Technology Licensing Office is
to bring about, through technology licensing, commercial investment
in the development of inventions and discoveries flowing from research
at the Massachusetts Institute of Technology, Lincoln Laboratory,
and the Whitehead Institute. It is through these investments-and
the economic development and new products that follow from them
– that university technology provides direct benefits to the
public.
We grant licenses of our patented and copyrighted
inventions to existing and startup companies that demonstrate the
technical and financial capabilities to develop our early-stage
technology into commercially successful products. Exclusive licenses
are common, and encourage investment through intellectual property
protection for the licensee.
The M.I.T. Technology Licensing Office is a fully
integrated component of the Massachusetts Institute of Technology
– one of the world’s leading research institutions in
the sciences and engineering. Our office manages the transition
between research results and licenses for the commercial development
of products. At any one time we have four to five hundred patents
pending, and about half our technologies are licensed before a patent
issues .
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Merrimack Pharmaceuticals, Inc., is a biotechnology
company focused on the discovery and development of drugs for the
treatment of immunological and autoimmune diseases, many of which
have only limited or problematic therapeutic options. The company_s
proprietary _network biology_ approach to drug discovery combines
next-generation proteomic technologies with an informed biological
perspective to evaluate the complex protein pathways and cellular
processes that cause disease. Merrimack believes it can address
many of the inefficiencies in current discovery approaches and improve
drug-target validation, increase quality lead identification and
speed the development of novel, effective and safe therapeutics.
Merrimack is a privately held company based in Cambridge, Massachusetts.
For additional information, please visit www.merrimackpharma.com.
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Millennium was founded in 1993 with a vision that
still drives us today: to transcend the limits of medicine.sm We
believe that by applying the methods of leading science to the art
of drug discovery, we will develop breakthrough products that will
fundamentally change the practice of medicine.
Beginning in 1994, Millennium created more than
20 strategic alliances with leading pharmaceutical and biotechnology
companies. These alliances provided Millennium with close to $2
billion of committed funding that we used to develop and enhance
our pipeline. With an innovative, integrated science and technology
platform, expertise in drug-target discovery, and industry-leading
partnerships, the company was geared to prime the product pipeline.
Through transformational mergers and acquisitions,
Millennium continued to advance toward the goal of building a leading
biopharmaceutical company. A merger with Leukosite in 1999 brought
the company its first drug close to market, Campath® (alemtuzumab)
Injection, and additional investigational drugs in clinical trials.
In February 2002, a merger with COR Therapeutics
— among the largest such mergers in the history of the biotech
industry — helped to further solidify our standing as a leading
biopharmaceutical company. In addition to creating a strong pipeline
of novel therapeutics, the merger added cardiovascular research
and drug development to the Company’s other key therapeutic
areas: oncology and inflammation. The merger also brought INTEGRILIN®
(eptifibatide) Injection, a market-leading intravenous anti-platelet
drug for patients with severe cardiovascular diseases, into the
Millennium fold.
As Millennium celebrated its tenth anniversary in
2003, the company reached new heights. VELCADE® (bortezomib)
for Injection was launched in May for the treatment of relapsed
and refractory multiple myeloma. VELCADE — the first FDA approved
proteasome inhibitor reached the market in record time and represents
the first treatment in more than a decade to be approved for patients
with multiple myeloma — a cancer of the blood.
Today, Millennium has two leading products, proven
commercial capabilities, and many product candidates in varying
stages of development. We are continually evolving to ensure that
our research and development efforts stay current with the demand
for new diagnostic and therapeutic products that will make a genuine
difference in patient’s lives.
www.mlnm.com
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Established in 1994, Monument Group is a specialized
placement agent whose sole business is providing superior alternative
investment opportunities to institutional investors. Each of the
firm’s principals has extensive “buy-side” experience,
either as consultants or investors. Since its formation, the firm
has successfully undertaken transaction structuring and placement
assignments for a variety of high-quality investment firms, encompassing
a diverse range of alternative asset classes including venture capital,
buyouts, distressed securities, special situations, oil & gas,
mezzanine/subordinated debt, real estate and international private
equity.
www.monumentgroup.com
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MPM Capital is the world’s largest dedicated
investor in life sciences. With committed capital under active management
of more than $2.1 billion, MPM is uniquely structured to invest
globally in healthcare innovation. In addition to its BioVentures
family of venture capital funds, MPM invests in the public markets
through its BioEquities hedge fund. Primarily in biotechnology,
but also in medical devices and biopharmaceuticals, MPM has seamlessly
integrated private and public equity products to target innovation
in healthcare and, thereby, deliver exceptional returns to investors.
The MPM BioVentures and MPM BioEquities family of funds are two
distinctly different but highly complementary investment vehicles.
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The NIH Office of Technology Transfer (OTT) evaluates,
protects, monitors, and manages the NIH invention portfolio to carry
out the mandates of the Federal Technology Transfer Act of 1986.
This is largely accomplished through overseeing patent prosecution,
negotiating and monitoring licensing agreements, and providing oversight
and central policy review of Cooperative Research and Development
Agreements. OTT also manages the patent and licensing activities
for the Food and Drug Adminstration (FDA). OTT is responsible for
the central development and implementation of technology transfer
policies for four research components of the PHS — the NIH,
the FDA, and the Centers for Disease Control and Prevention, and
the Agency for Healthcare Research and Quality.
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NIBCapital Bank has the ambition to become one of
the leading independent Merchant Banks in Northwestern Europe with
a worldwide distribution network. The strong AA rating, the financially
strong and committed shareholders ABP and PGGM and the compact organisation
make for a uniquely positioned bank. The most important activities
are corporate finance, risk management and structured investment
solutions. The client focus is reflected in a platform of Client
Sector Teams. A strong personal commitment to clients and teamwork
are anchored in a multidisciplinary approach of product- and sector
specialists. This leads to appropriate custom-made solutions in
teams for our clients. The partnership structure and the high level
of professionalism translates back in creativity and quality. The
bank focuses on corporates, financial institutions, institutional
investors and family offices.
www.nibcapital.com
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Nomura’s biotech and healthcare research team
provides extensive coverage for many of Europe's Mediscience companies.
Mediscience is a broadly categorised group of lifescience or health-related
companies that have the potential to grow rapidly. This diverse
group of small to mid-cap companies includes biotechnology, healthcare,
medical device, medical technology and medical services company
sectors across Europe with a prime focus on the UK. The team specialises
in identifying key industry themes across the world from a top down
view. We then investigate individual companies that could benefit
from these themes using a bottom-up view. We look for individual
companies that are fundamentally undervalued, primarily based on
risk adjusted net present value estimates of cash flow. In these
very subjective areas, we also pay particular attention to relative
valuations such as comparative analysis and non-numerical risk factors
such as management and competition in drug specific areas. Nomura's
team has a long established and externally recognised track record
in these sectors: number one for the last three years in the Reuters
smaller companies survey, according to both fund managers and finance
directors. Individual responsibilities have evolved into the following
broad categories.
www.nomura.com
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Oxford Bioscience Partners (OBP) is a life science
venture capital firm that provides equity financing and management
assistance to start-up and early-stage, entrepreneurial-driven companies
in the bioscience and healthcare industries. The General Partners
of OBP currently manage venture funds with combined committed capital
of more than $800 million.
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Polaris Venture Partners is an early stage venture
capital firm with two locations in the U.S: Boston, Massachusetts,
and Seattle, Washington. Polaris currently has over $2.0 billion
under management with investments in more than 50 diversified information
technology and medical technology companies. Through its philosophy
of active lead investing and partnering with early and revenue stage
companies, the firm’s team of experienced venture investors
and technology executives has generated triple-digit returns from
investments across its four funds.
Polaris invests two-thirds of its capital in information
technology and one-third in medical technology companies. Within
the information technology sector, Polaris has invested in companies
with expertise in Internet infrastructure, e-commerce, telephony,
and network hardware and software. In the medical technology sector,
the firm has invested in companies focused on medical devices, pharmaceuticals,
genomics, and health care services.
Polaris Venture Partners has more than 50 companies
in its portfolio, including industry leaders such as Akamai Technologies,
Allaire Corporation, Avici, decode Genetics, and Paradigm Genetics.
Headquarters: 1000 Winter Street, Suite 3350
Waltham, MA 02451
Tel: 781 290 0770 • Fax: 781 290 0880
www.polarisventures.com
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Schroder Ventures Life Sciences ("SVLS")
was established in 1993 and currently has offices in Boston, London
and San Francisco, which allows us to take advantage of the global
nature of life sciences opportunities. The SVLS team is comprised
of 24 professionals, with a deep base of life science investment,
operational, scientific and clinical experience.
SVLS advises three private equity funds with total
commitments of approximately $640m, focused on providing seed, start-up,
early stage and expansion capital to life sciences companies primarily
in the US and Europe. In addition, SVLS advises the International
Biotechnology Trust (IBT) plc, a publicly quoted investment trust
listed on the London Stock Exchange (IBT), with a total net asset
value of approximately $56m (as at 30 June 2002). The majority of
IBT's investments are in quoted companies.
Funds advised by SVLS are able to invest in all
stages in the development of a life science business. SVLS provides
hands-on scientific, advisory and financial support to its portfolio
companies.
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Sofinnova Partners is a leading European venture
capital firm dedicated to investing in early stage companies in
Life Sciences and Information Technologies.
Founded in Paris in 1972, Sofinnova Partners has
been a fully independent partnership since 1997. We have €
500 million of active funds under management, including : Sofinnova
Capital II (1994), a € 47 million fund ; Sofinnova Capital
III (1998), a € 120 million fund ; Sofinnova Capital IV (closed
in March 2001), a € 330 million fund.
Our target for Sofinnova Capital IV is to invest
in 30 ambitious technology start-up companies. We expect that Sofinnova
Capital IV’s investments will be balanced between the life
sciences and IT sectors, with 50%of the fund invested in France
and 50% in the rest of Europe and the US.
Life sciences sector
Sofinnova Partners focuses on biopharmaceuticals
and medical devices opportunities, which address large unmet clinical
needs for example cardiovascular, central nervous system, oncology
and infectious diseases. Sofinnova Partners invests very early in
its portfolio companies and support them in a step by step approach
throughout their development cycle, with investments ranging from
€ 0.5 to € 15 million. Over the past five years, Sofinnova
Partners has been a lead or co-lead investor in companies such as
Actelion, Genset, Nicox, Novuspharma, Oxford Molecular and IDM.
Sofinnova Partners’ most recent investments include : Biolipox
(Sweden), Ablynx (Belgique), Cellzome (Germany), Faust Pharmaceutical
(France), Carex (France), Promed (Austria) Addex (Switzerland) and
Neuro3D (France).
For more information, please visit www.sofinnova.fr
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Founded in 1876, Womble Carlyle Sandridge &
Rice, PLLC has a 127-year history of helping business leaders address
evolving challenges and uncover new opportunities. One of the fastest
growing law firms in the United States, Womble Carlyle has more
than 450 lawyers and specialized professionals serving clients worldwide
from offices located in Washington, DC; Northern Virginia; London
(UK), Research Triangle Par; Atlanta; and other offices throughout
the southeastern United States.
The Firm’s Life Science practice represents
one of its most dynamic and diversified groups, serving both national
and international pharmaceutical, biotech, and other drug development
and medical device companies, health care and managed care providers,
related information technology companies, venture capital firms
and equity funds. The Firm’s BioAlliance Practice, a unique,
multi-disciplinary, industry-oriented group, provides bio-pharma
clients with legal and related business development expertise for
their corporate partnering activities. The Firm’s Technology
& Commerce Group, comprised of over 80 intellectual property
attorneys, includes over 40 patent prosecution lawyers and, together,
with another 30 specialized litigators, handle sophisticated infringement
litigation and an increasing number of licensing disputes for clients
worldwide.
Womble Carlyle also represents businesses, agencies
and foundations in other industry sectors including financial services,
telecommunications, software, manufacturing, transportation, energy,
government relations, construction, and education. The legal community,
and particularly the healthcare industry, has recognized Womble
Carlyle for its innovative use of information technology, designed
to facilitate the delivery of legal services and provide alternative
solutions for improving management efficiencies and profitability.
www.wcsr.com
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